Europe Market Report for Spinal Vertebral Compression Fracture 2017 - MedCore

TABLE OF CONTENTS I
LIST OF FIGURES XIII
LIST OF CHARTS XVI
EXECUTIVE SUMMARY 1
EUROPE SPINAL IMPLANTS AND VCF MARKET OVERVIEW 1
COMPETITIVE ANALYSIS 3
MARKET TRENDS 5
MARKET DEVELOPMENTS 7
PROCEDURE NUMBERS 8
MARKETS INCLUDED 11
KEY REPORT UPDATES 14
VERSION HISTORY 14
RESEARCH METHODOLOGY 15
1.1 RESEARCH SCOPE 15
1.2 IDATA’S 9-STEP METHODOLOGY 15
Step 1: Project Initiation & Team Selection 15
Step 2: Prepare Data Systems and Perform Secondary Research 17
Step 3: Preparation for Interviews & Questionnaire Design 18
Step 4: Performing Primary Research 19
Step 5: Research Analysis: Establishing Baseline Estimates 21
Step 6: Market Forecast and Analysis 22
Step 7: Identify Strategic Opportunities 24
Step 8: Final Review and Market Release 25
Step 9: Customer Feedback and Market Monitoring 26
DISEASE OVERVIEW 27
2.1 INTRODUCTION 27
2.1.1 Degenerative Disc Disease 27
2.1.1.1 Disc Herniation 27
2.1.1.2 Stenosis 28
2.1.1.3 Spondyloisthesis 29
2.1.1.4 Arthritis 29
2.1.2 Spinal Deformities 29
2.1.2.1 Scoliosis 29
2.1.2.2 Kyphosis and Lordosis 30
2.1.3 Trauma and Tumor 31
2.1.4 Vertebral Compression Fractures 31
2.1.4.1 Osteoporosis 31
2.1.4.2 Vertebral Compression Fractures 32
PRODUCT ASSESSMENT 33
3.1 PRODUCT PORTFOLIOS 33
3.1.1 Vertebral Compression Fracture Devices 33
3.1.1.1.1 Percutaneous Vertebroplasty 33
3.1.1.1.2 Percutaneous Vertebral Augmentation Including Kyphoplasty 34
3.1 FDA RECALLS 37
3.1.1 Alphatec Spine 37
3.1.2 DePuy Synthes 37
3.1.3 Medtronic 38
3.1.4 Orthofix 39
3.1.5 Stryker 40
3.1.6 Zimmer Biomet 41
3.2 CLINICAL TRIALS 42
3.2.1 DePuy Synthes 42
3.2.2 Globus Medical 42
3.2.3 K2M 43
3.2.4 Medtronic 44
3.2.5 Stryker 45
3.2.6 Zimmer Biomet 46
COUNTRY PROFILES 47
4.1 INTRODUCTION 47
4.1.1.1 Population 47
4.1.1.2 Median Age 47
4.1.1.3 GDP Per Capita 47
4.1.1.4 Price Index 47
4.2 GERMANY 48
4.3 FRANCE 49
4.4 UNITED KINGDOM 50
4.5 ITALY 51
4.6 SPAIN 52
4.7 BENELUX 53
4.8 SCANDINAVIA 54
4.9 AUSTRIA 55
4.10 SWITZERLAND 56
4.11 PORTUGAL 57
VERTEBRAL COMPRESSION FRACTURE MARKET 58
5.1 INTRODUCTION 58
5.1.1 Percutaneous Vertebroplasty 58
5.1.2 Percutaneous Vertebral Augmentation including Kyphoplasty 59
5.2 MARKET OVERVIEW 61
5.3 MARKET ANALYSIS AND FORECAST 65
5.3.1 Total Vertebral Compression Fracture Market 65
5.3.2 Vertebroplasty Market 72
5.3.3 Percutaneous Vertebral Augmentation Market 80
5.4 DRIVERS AND LIMITERS 88
5.4.1 Market Drivers 88
5.4.2 Market Limiters 89
5.5 COMPETITIVE MARKET SHARE ANALYSIS 92
ABBREVIATIONS 96
APPENDIX: COMPANY PRESS RELEASES 98

List of Chart
Chart 1 1: Spinal Implants and VCF Market by Segment, Europe, 2013 – 2023 2
Chart 1 2: Spinal Implants and VCF Market Overview, Europe, 2016 & 2023 2
Chart 4 1: Country Profile, Germany, 2016 48
Chart 4 2: Country Profile, France, 2016 49
Chart 4 3: Country Profile, United Kingdom, 2016 50
Chart 4 4: Country Profile, Italy, 2016 51
Chart 4 5: Country Profile, Spain, 2016 52
Chart 4 6: Country Profile, Benelux, 2016 53
Chart 4 7: Country Profile, Scandinavia, 2016 54
Chart 4 8: Country Profile, Austria, 2016 55
Chart 4 9: Country Profile, Switzerland, 2016 56
Chart 4 10: Country Profile, Portugal, 2016 57
Chart 5 1: Vertebral Compression Fracture Market by Segment, Europe, 2013 – 2023 63
Chart 5 2: Vertebral Compression Fracture Market Breakdown, Europe, 2016 64
Chart 5 3: Vertebral Compression Fracture Market Breakdown, Europe, 2023 64
Chart 5 4: Total Vertebral Compression Fracture Market, Europe, 2013 – 2023 66
Chart 5 5: Vertebroplasty Market, Europe, 2013 – 2023 74
Chart 5 6: Percutaneous Vertebral Augmentation Market, Europe, 2013 – 2023 82
Chart 5 7: Leading Competitors, Vertebral Compression Fracture Market, Europe, 2016 95

List of Figures
Figure 1 1: Spinal Implants and VCF Market Share Ranking by Segment, Europe, 2016 (1 of 2) 3
Figure 1 2: Spinal Implants and VCF Market Share Ranking by Segment, Europe, 2016 (2 of 2) 3
Figure 1 3: Companies Researched in this Report, Europe, 2016 4
Figure 1 4: Factors Impacting the Spinal Implants and VCF Market by Segment, Europe (1 of 2) 5
Figure 1 5: Factors Impacting the Spinal Implants and VCF Market by Segment, Europe (2 of 2) 6
Figure 1 6: Recent Events in the Spinal Implants and VCF Market, Europe, 2014 – 2017 7
Figure 1 7: Spinal Implants and VCF Procedures Covered, Europe, 2016 (1 of 3) 8
Figure 1 8: Spinal Implants and VCF Procedures Covered, Europe, 2016 (2 of 3) 9
Figure 1 9: Spinal Implants and VCF Procedures Covered, Europe, 2016 (3 of 3) 10
Figure 1 10: Spinal Implants and VCF Markets Covered, Europe, 2016 (1 of 3) 11
Figure 1 11: Spinal Implants and VCF Markets Covered, Europe, 2016 (2 of 3) 12
Figure 1 12: Spinal Implants and VCF Markets Covered, Europe, 2016 (3 of 3) 13
Figure 1 13: Key Report Updates 14
Figure 1 14: Version History 14
Figure 3 1: Vertebral Compression Fracture Devices by Company 36
Figure 3 2: Class 2 Device Recall Alphatec Spine 37
Figure 3 3: Class 2 Device Recall DePuy Synthes 37
Figure 3 4: Class 2 Device Recall DePuy Synthes 37
Figure 3 5: Class 2 Device Recall Medtronic 38
Figure 3 6: Class 2 Device Recall Medtronic 38
Figure 3 7: Class 2 Device Recall Medtronic 38
Figure 3 8: Class 2 Device Recall Medtronic 39
Figure 3 9: Class 2 Device Recall Orthofix 39
Figure 3 10: Class 2 Device Recall Orthofix 39
Figure 3 11: Class 2 Device Recall Orthofix 40
Figure 3 12: Class 2 Device Recall Orthofix 40
Figure 3 13: Class 2 Device Recall Stryker 40
Figure 3 14: Class 2 Device Recall Stryker 41
Figure 3 15: Class 2 Device Recall Zimmer Biomet 41
Figure 3 16: An ACDF Multi-Center Study Using ViviGen Cellular Bone Matrix 42
Figure 3 17: A Retrospective Study Using CALIBER® TLIF Expandable Spacer in the Treatment of DDD: 2 Year Follow-up. 42
Figure 3 18: Comparing Pedicle Screw Systems for the Treatment of Adolescent Paediatric Spine Deformity 43
Figure 3 19: A Prospective, 5-Year Global Study on MAST™ 44
Figure 3 20: Spinal Cord Stimulation to Treat Post-operative Atrial Fibrillation (SCS-PAF) 44
Figure 3 21: OLIF25™ /OLIF51™ Study 45
Figure 3 22: AccuLIF® PROSPECTIVE PATIENT OUTCOMES STUDY (APROPOS) 45
Figure 3 23: Post-Market Surveillance Study of the TM Ardis Interbody Fusion System 46
Figure 5 1: Vertebral Compression Fracture Market by Segment, Europe, 2013 – 2023 (€M) 61
Figure 5 2: Vertebral Compression Fracture Market by Segment, Europe, 2013 – 2023 (US$M) 62
Figure 5 3: Total Vertebral Compression Fracture Market, Europe, 2013 – 2023 65
Figure 5 4: Units Sold by Country, Total Vertebral Compression Fracture Market, Europe, 2013 – 2023 67
Figure 5 5: Average Selling Price by Country, Total Vertebral Compression Fracture Market, Europe, 2013 – 2023 (€) 68
Figure 5 6: Average Selling Price by Country, Total Vertebral Compression Fracture Market, Europe, 2013 – 2023 (US$) 69
Figure 5 7: Market Value by Country, Total Vertebral Compression Fracture Market, Europe, 2013 – 2023 (€M) 70
Figure 5 8: Market Value by Country, Total Vertebral Compression Fracture Market, Europe, 2013 – 2023 (US$M) 71
Figure 5 9: Vertebroplasty Market, Europe, 2013 – 2023 73
Figure 5 10: Units Sold by Country, Vertebroplasty Market, Europe, 2013 – 2023 75
Figure 5 11: Average Selling Price by Country, Vertebroplasty Market, Europe, 2013 – 2023 (€) 76
Figure 5 12: Average Selling Price by Country, Vertebroplasty Market, Europe, 2013 – 2023 (US$) 77
Figure 5 13: Market Value by Country, Vertebroplasty Market, Europe, 2013 – 2023 (€M) 78
Figure 5 14: Market Value by Country, Vertebroplasty Market, Europe, 2013 – 2023 (US$M) 79
Figure 5 15: Percutaneous Vertebral Augmentation Market, Europe, 2013 – 2023 81
Figure 5 16: Units Sold by Country, Percutaneous Vertebral Augmentation Market, Europe, 2013 – 2023 83
Figure 5 17: Average Selling Price by Country, Percutaneous Vertebral Augmentation Market, Europe, 2013 – 2023 (€) 84
Figure 5 18: Average Selling Price by Country, Percutaneous Vertebral Augmentation Market, Europe, 2013 – 2023 (US$) 85
Figure 5 19: Market Value by Country, Percutaneous Vertebral Augmentation Market, Europe, 2013 – 2023 (€M) 86
Figure 5 20: Market Value by Country, Percutaneous Vertebral Augmentation Market, Europe, 2013 – 2023 (US$M) 87
Figure 5 21: Drivers and Limiters, Vertebral Compression Fracture Market, Europe, 2016 91
Figure 5 22: Leading Competitors, Vertebral Compression Fracture Market, Europe, 2016 94